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Question 1 of 20
1. Question
Vasoconstriction is caused by several regulatory molecules, which include:
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Question 2 of 20
2. Question
Warfarin is classified as a vitamin K antagonist. The factors that are impacted by warfarin therapy are:
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Question 3 of 20
3. Question
When a patent is placed on warfarin therapy, the first factor that will be decreased is:
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Question 4 of 20
4. Question
A patient with a positive family history of bleeding presents to the ED with the results shown in this table:
test     Â
result           Â
reference range
aPTTÂ Â Â Â Â
29.5 seconds
25-35 seconds
PTÂ Â Â Â Â Â Â Â Â
19.2 seconds     Â
10.5-12.5 seconds
The patient is not on any medication and so is likely to be deficient in factor:
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Question 5 of 20
5. Question
Hageman factor (XII) is involved in each of the following reactions except:
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Question 6 of 20
6. Question
The most potent plasminogen activator in the contact phase of coagulation is:
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Question 7 of 20
7. Question
The activation of plasminogen to plasmin resulting in the degradation of fibrin occurs by:
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Question 8 of 20
8. Question
How does tissue factor pathway inhibitor inhibit coagulation?
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Question 9 of 20
9. Question
An inhibitor of plasmin activity is:
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Question 10 of 20
10. Question
Antithrombin inhibits factors:
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Question 11 of 20
11. Question
The propagation phase of the in vivo coagulation model includes:
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Question 12 of 20
12. Question
In the cell-based model of coagulation the intrinsic pathway operates on the:
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Question 13 of 20
13. Question
A new oral anticoagulant apixaban has been given to a patient who was previously on warfarin. This drug directly inhibits:
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Question 14 of 20
14. Question
The anticoagulant that directly inhibits thrombin is:
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Question 15 of 20
15. Question
A patient who presents with renal impairment is being started on oral anticoagulant therapy. The DOAC that should be avoided would be:
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Question 16 of 20
16. Question
In secondary hemostasis, coagulation proteins become activated to form a fibrin clot. Prior to these proteins being activated, their inactive proenzymes are known as:
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Question 17 of 20
17. Question
Alpha granules are found on the platelet in the:
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Question 18 of 20
18. Question
Which of the following best represents the 3 steps of normal hemostasis (in order)?
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Question 19 of 20
19. Question
Which of the following platelet antigens is the receptor for collagen?
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Question 20 of 20
20. Question
Which platelet surface antigen acts as the receptor for fibrinogen?
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